What kind of wheel does your hedgie have?
Have you checked the feet for any abrasions or wounds?
How many nights has he gone without wheeling?
Has there been any change in his eating habits? How does his stool and urine look (you would be looking for green colored stool and possibly blood in the urine).

Have you checked the feet for any abrasions or wounds?
How many nights has he gone without wheeling?
Has there been any change in his eating habits? How does his stool and urine look (you would be looking for green colored stool and possibly blood in the urine).