Cloud and i regularly take 4 hour drives from Fla to SC and back. I put him in a cat carrier with a fleece liner and a folded up bath towel. He will usually hunker down in the bathtowel and sleep the entire ride. I do have food and a little bit of water avaiable just in case he wakes up though 
Also, i make sure to strap him in! one time i didnt and i took a turn too sharply and his carrier tipped. he wasnt too happy, lol!
Also, i make sure to strap him in! one time i didnt and i took a turn too sharply and his carrier tipped. he wasnt too happy, lol!