It could actually be a good thing for your hedgehog to get used to two different caretakers. It’s not hard for them to do, but many a time a hedgehog will bond solely to one person and socialize differently than to those who have multiple people taking care of them. I would recommend asking your mom to take him out every now and then even to just sleep in a sack on the couch or if she’s doing work at a desk have him near her on the desk. She doesn’t have to handle him too much, but it will still be better than nothing for a weekend. I would also keep a radio on throughout the weekend at a soft setting just so she stays used to noise; there are also a lot of hedgehogs (mine included) that got used to dead silence when they were young and are VERY timid around sounds as an adult. Just some suggestions.
Hope this helps 🙂